Name
Title | ||
|---|---|---|
Multimodal Mechanistic Signatures for Neurodegenerative Diseases (NeuroMMSig): a web server for mechanism enrichment. |
Abstract | ||
|---|---|---|
The concept of a 'mechanism-based taxonomy of human disease' is currently replacing the outdated paradigm of diseases classified by clinical appearance. We have tackled the paradigm of mechanism-based patient subgroup identification in the challenging area of research on neurodegenerative diseases. We have developed a knowledge base representing essential pathophysiology mechanisms of neurodegenerative diseases. Together with dedicated algorithms, this knowledge base forms the basis for a 'mechanism-enrichment server' that supports the mechanistic interpretation of multiscale, multimodal clinical data. Availability and implementation: NeuroMMSig is available at http://neurommsig.scai.fraunhofer.de/ Contact: martin. hofmann-apitius@scai.fraunhofer.de Supplementary information: Supplementary data are available at Bioinformatics online. |
Year | DOI | Venue |
|---|---|---|
2017 | 10.1093/bioinformatics/btx399 | BIOINFORMATICS |
Field | DocType | Volume |
Data mining,World Wide Web,Computer science,Software,Knowledge base,Bioinformatics,Human disease,The Internet,Web server | Journal | 33 |
Issue | ISSN | Citations |
22 | 1367-4803 | 4 |
PageRank | References | Authors |
0.59 | 2 | 10 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Daniel Domingo-Fernández | 1 | 9 | 5.48 |
| alpha tom kodamullil | 2 | 15 | 3.08 |
| Anandhi Iyappan | 3 | 6 | 1.00 |
| mufassra naz | 4 | 7 | 1.22 |
| Mohammad Asif Emon | 5 | 4 | 0.59 |
| Tamara Raschka | 6 | 6 | 1.67 |
| Reagon Karki | 7 | 11 | 1.05 |
| Stephan Springstubbe | 8 | 12 | 1.20 |
| Christian Ebeling | 9 | 265 | 25.14 |
| Martin Hofmann-Apitius | 10 | 372 | 30.08 |