Title
AZPharm MetaAlert: A Meta-learning Framework for Pharmacovigilance.
Abstract
Pharmacovigilance is the research related to the detection, assessment, understanding, and prevention of adverse drug events. Despite the research efforts in pharmacovigilance in recent year, current approaches are insufficient in detecting adverse drug reaction (ADR) signals timely across different datasets. In this study, we develop an integrated and high-performance AZ Pharm Meta-Alert framework for efficient and accurate post-approval pharmacovigilance. Our approach extracts adverse drug events from patient social media, electronic health records, and FDA's Adverse Event Reporting System (FAERS) and integrates ADR signals with stacking and bagging methods. Experiment results show that our approach achieves 71% in precision, 90% in recall, and 80% in f-measure for ADR signal detection and significantly outperforms the traditional signal detection methods.
Year
DOI
Venue
2016
10.1007/978-3-319-59858-1_14
Lecture Notes in Computer Science
Keywords
DocType
Volume
Pharmacovigilance,Adverse drug event,Meta-learning,Deep-learning,Drug safety surveillance
Conference
10219
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
0
2
Name
Order
Citations
PageRank
ying liu136446.92
Hsinchun Chen29569813.33