Name
Abstract | ||
|---|---|---|
ChannelsDB (http://ncbr.muni.cz/ChannelsDB) is a database providing information about the positions, geometry and physicochemical properties of channels (pores and tunnels) found within biomacromolecular structures deposited in the Protein Data Bank. Channels were deposited from two sources; from literature using manual deposition and from a software tool automatically detecting tunnels leading to the enzymatic active sites and selected cofactors, and transmembrane pores. The database stores information about geometrical features (e.g. length and radius profile along a channel) and physicochemical properties involving polarity, hydrophobicity, hydropathy, charge and mutability. The stored data are interlinked with available UniProt annotation data mapping known mutation effects to channel-lining residues. All structures with channels are displayed in a clear interactive manner, further facilitating data manipulation and interpretation. As such, ChannelsDB provides an invaluable resource for research related to deciphering the biological function of biomacromolecular channels. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1093/nar/gkx868 | NUCLEIC ACIDS RESEARCH |
Field | DocType | Volume |
Software tool,Biology,Data mapping,UniProt,Data manipulation language,Protein Data Bank,Database,Protein structure | Journal | 46 |
Issue | ISSN | Citations |
D1 | 0305-1048 | 2 |
PageRank | References | Authors |
0.37 | 21 | 8 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Lukáš Pravda | 1 | 11 | 0.85 |
| David Sehnal | 2 | 75 | 8.73 |
| Radka Svobodová Vareková | 3 | 79 | 12.54 |
| Veronika Navrátilová | 4 | 42 | 2.89 |
| Dominik Toušek | 5 | 4 | 1.46 |
| Karel Berka | 6 | 66 | 6.92 |
| Michal Otyepka | 7 | 146 | 10.48 |
| Jaroslav Koca | 8 | 193 | 25.16 |