Name
Title | ||
|---|---|---|
The heterogeneity of the left dorsal premotor cortex evidenced by multimodal connectivity-based parcellation and functional characterization. |
Abstract | ||
|---|---|---|
Despite the common conception of the dorsal premotor cortex (PMd) as a single brain region, its diverse connectivity profiles and behavioral heterogeneity argue for a differentiated organization of the PMd. A previous study revealed that the right PMd is characterized by a rostro-caudal and a ventro-dorsal distinction dividing it into five subregions: rostral, central, caudal, ventral and dorsal. The present study assessed whether a similar organization is present in the left hemisphere, by capitalizing on a multimodal data-driven approach combining connectivity-based parcellation (CBP) based on meta-analytic modeling, resting-state functional connectivity, and probabilistic diffusion tractography. The resulting PMd modules were then characterized based on multimodal functional connectivity and a quantitative analysis of associated behavioral functions. Analyzing the clusters consistent across all modalities revealed an organization of the left PMd that mirrored its right counterpart to a large degree. Again, caudal, central and rostral modules reflected a cognitive-motor gradient and a premotor eye-field was found in the ventral part of the left PMd. In addition, a distinct module linked to abstract cognitive functions was observed in the rostro-ventral left PMd across all CBP modalities, implying greater differentiation of higher cognitive functions for the left than the right PMd. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1016/j.neuroimage.2017.02.034 | NeuroImage |
Keywords | Field | DocType |
Precentral gyrus,eye-field,meta-analytic connectivity modeling,probabilistic diffusion tractography,fMRI | Developmental psychology,Ventral part,Neuroscience,Lateralization of brain function,Dorsum,Premotor cortex,Diffusion Tractography,Psychology,Precentral gyrus,Cognition | Journal |
Volume | ISSN | Citations |
170 | 1053-8119 | 8 |
PageRank | References | Authors |
0.55 | 24 | 14 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Sarah Genon | 1 | 21 | 2.30 |
| Andrew T. Reid | 2 | 60 | 6.02 |
| Hai Li | 3 | 2435 | 208.37 |
| Lingzhong Fan | 4 | 51 | 5.51 |
| Veronika I. Müller | 5 | 30 | 3.70 |
| Edna C. Cieslik | 6 | 44 | 3.38 |
| Felix Hoffstaedter | 7 | 46 | 5.38 |
| Robert Langner | 8 | 105 | 5.87 |
| Christian Grefkes | 9 | 171 | 16.40 |
| Angela R. Laird | 10 | 858 | 48.19 |
| Peter T. Fox | 11 | 929 | 63.79 |
| T. Jiang | 12 | 1419 | 128.59 |
| Katrin Amunts | 13 | 389 | 37.30 |
| Simon B. Eickhoff | 14 | 1297 | 79.68 |