Title
Towards Clinic-Friendly Solutions For Patient Trials In Breast Cancer Phase Contrast Imaging
Abstract
Phase-contrast imaging of the breast is expected to deliver significantly improved image quality and diagnostic value at a reduced radiation dose compared to present-day 2D X-ray mammography, digital breast tomosynthesis (DBT) and computed tomography (CT) and become a viable method for early diagnosis of breast cancer in women. This paper builds upon the evaluation of a novel protocol to evaluate 3D mammographic phase contrast imaging for the detection of breast cancer undertaken with a purpose designed phantom and selected breast cancer specimens. Following evaluation, propagation-based phase contrast imaging was demonstrated to have high contrast to noise ratio alongside an important reduction in radiation dose. The challenge now is to shift the focus of research to real clinic solutions, with the worldfirst demonstration of X-ray in-line full field phase-contrast mammographic tomography (PCT) with cancer patients through an international collaboration of a multi-disciplinary team.
Year
DOI
Venue
2018
10.1117/12.2316498
14TH INTERNATIONAL WORKSHOP ON BREAST IMAGING (IWBI 2018)
Keywords
DocType
Volume
Breast CT, phase-contrast, synchrotron radiation, patients, cancer imaging
Conference
10718
ISSN
Citations 
PageRank 
0277-786X
0
0.34
References 
Authors
0
11