Title | ||
---|---|---|
High resolution volumetric imaging of primary and secondary tumor spheroids using multi-angle Light Sheet Fluorescence Microscopy (LSFM). |
Abstract | ||
---|---|---|
Breast cancer and Glioblastoma brain cancer are severe malignancies with poor prognosis. In this study, primary Glioblastoma and secondary breast cancer spheroids are formed and treated with the well-known Temozolomide and Doxorubicin chemotherapeutics, respectively. High resolution imaging of both primary and secondary cancer cell spheroids is possible using a custom multi-angle Light Sheet Fluorescence Microscope. Such a technique is successful in realizing preclinical drug screening, while enables the discrimination among physiologic tumor parameters. |
Year | DOI | Venue |
---|---|---|
2018 | 10.1109/EMBC.2018.8512388 | EMBC |
Field | DocType | Volume |
Computer vision,Fluorescence microscope,Spheroid,Breast cancer,Temozolomide,Computer science,Light sheet fluorescence microscopy,Doxorubicin,Cancer research,Artificial intelligence,Microscopy,Cancer | Conference | 2018 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
7 |
Name | Order | Citations | PageRank |
---|---|---|---|
Stylianos E. Psycharakis | 1 | 0 | 0.34 |
Evangelos Liapis | 2 | 0 | 0.34 |
Athanasios Zacharopoulos | 3 | 0 | 1.01 |
Mariam-Eleni Oraiopoulou | 4 | 0 | 0.34 |
Joseph Papamatheakis | 5 | 0 | 0.34 |
Vangelis Sakkalis | 6 | 110 | 23.68 |
Giannis Zacharakis | 7 | 9 | 3.02 |