Name
Title | ||
|---|---|---|
ANTENNA, a Multi-Rank, Multi-Layered Recommender System for Inferring Reliable Drug-Gene-Disease Associations: Repurposing Diazoxide as a Targeted Anti-Cancer Therapy. |
Abstract | ||
|---|---|---|
Existing drug discovery processes follow a reductionist model of “one-drug-one-gene-one-disease,” which is inadequate to tackle complex diseases involving multiple malfunctioned genes. The availability of big omics data offers opportunities to transform drug discovery process into a new paradigm of systems pharmacology that focuses on designing drugs to target molecular interaction networks instea... |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1109/TCBB.2018.2812189 | IEEE/ACM Transactions on Computational Biology and Bioinformatics |
Keywords | Field | DocType |
Drug delivery,Bioinformatics,Diseases,Genomics,Data analysis,Cancer,Data mining,Machine learning,Breast cancer,Predictive methods | Recommender system,Systems pharmacology,Drug discovery,Disease,Collaborative filtering,Targeted therapy,Repurposing,Biology,Bioinformatics,Big data | Journal |
Volume | Issue | ISSN |
15 | 6 | 1545-5963 |
Citations | PageRank | References |
1 | 0.35 | 0 |
Authors | ||
4 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Annie Wang | 1 | 1 | 0.35 |
| Hansaim Lim | 2 | 2 | 1.72 |
| Shu-Yuan Cheng | 3 | 1 | 0.35 |
| Lei Xie | 4 | 441 | 39.48 |