Title
[Regular Paper] EP-CapsNet: Extending Capsule Network with Inception Module for Electrophoresis Binary Classification
Abstract
Electrophoresis (EP) test separates protein components based on their density. Patterns exhibited by this test mostly show very close approximation, making it difficult to examine test results within a short amount of time as it has many variations of patterns and requires a significant amount of knowledge to discern them accurately. To help clinical examiners save time and produce consistent results, a new deeplearning model optimized for EP graphic images was developed. Extending recent work on capsule network, which is a stateof- the-art deep learning model, this study was carried out to develop a best-performing model in classifying abnormal and normal electrophoresis patterns. Instead of extracting features from the image, we used the whole slide image as an input to the classifier. This study used 39,484 electrophoresis 2D graph images and utilized capsule network as the foundation of the deep learning architecture to learn the images without data augmentation. The formulated models were compared for a multitude of performance metrics including accuracy, sensitivity, and specificity. Overall, the study results show that our proposed architecture EP-CapsNet, which combines capsule network with Google’s inception module, is the best performing model, outperforming the baseline and alternative models in almost all comparisons.
Year
DOI
Venue
2018
10.1109/BIBE.2018.00071
2018 IEEE 18th International Conference on Bioinformatics and Bioengineering (BIBE)
Keywords
Field
DocType
electrophoresis binary classification,electrophoresis test,protein components,test results,clinical examiners,consistent results,deep-learning model,state-of-the-art deep learning model,best-performing model,abnormal electrophoresis patterns,slide image,utilized capsule network,deep learning architecture,formulated models,architecture EP-CapsNet,alternative models,performance metrics,Google inception module,electrophoresis 2D graph images
Pattern recognition,Binary classification,Computer science,Electrophoresis,Artificial intelligence,Machine learning
Conference
ISSN
ISBN
Citations 
2159-5410
978-1-5386-5043-1
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Elizabeth Tobing100.34
Ashraf Murtaza200.34
Keejun Han3244.65
Mun Y. Yi4115058.52