Title | ||
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Shape-controlled production of alginate hydrogel-poly-L-lysine microcapsules based on electrodeposition method: Shape-controlled microcapsules |
Abstract | ||
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In this study, we describe a novel method of fabricating shape-controlled calcium alginate gel microcapsules. Alginate-poly-L-lysine (PLL) hydrogel microcapsules with predefined shapes were constructed based on electrodeposition method. Firstly, electrolysis of water in alginate solutions with calcium carbonate particles induced alginate gelation on micro-patterned electrode to form 2D gel structures. Then, these structures will be detached from the electrode surface and treated with the alginate-PLL microcapsules system. By passive control based on the micro-pattern geometric confinement and electrodeposition parameters, we succeeded in producing calcium alginate-PLL microcapsules with diverse shapes (such as sphere rod and cubic). The shape and size of the calcium alginate microcapsules could be tuned by adjusting the geometric design of micro-pattern on electrode and the apply voltage of electrodepostion. The preparation conditions of size- and shape-controlled calcium alginate-PLL microcapsules and influence factors were studied. This proposed method can lead to more accurate and creative studies of fabricating biocompatibility scaffold for tissue engineering. |
Year | DOI | Venue |
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2015 | 10.1109/IECON.2015.7392106 | IECON 2015 - 41st Annual Conference of the IEEE Industrial Electronics Society |
Keywords | Field | DocType |
Electrodeposition,Alginate-PLL,Microcapsules,Tissue engineering | Biomedical engineering,Biocompatibility,Calcium,Control theory,Electrolysis of water,Tissue engineering,Chemical engineering,Engineering,Calcium alginate,Lysine,Calcium carbonate,Electrode | Conference |
ISSN | Citations | PageRank |
1553-572X | 0 | 0.34 |
References | Authors | |
0 | 6 |
Name | Order | Citations | PageRank |
---|---|---|---|
Zeyang Liu | 1 | 0 | 1.69 |
Masaru Takeuchi | 2 | 9 | 18.01 |
Masahiro Nakajima | 3 | 15 | 16.33 |
Yasuhisa Hasegawa | 4 | 456 | 94.62 |
Toshio Fukuda | 5 | 2723 | 818.58 |
Qiang Huang | 6 | 266 | 91.95 |