Title
Detecting Essential Proteins Based on Network Topology, Gene Expression Data and Gene Ontology Information.
Abstract
The identification of essential proteins in protein-protein interaction (PPI) networks is of great significance for understanding cellular processes. With the increasing availability of large-scale PPI data, numerous centrality measures based on network topology have been proposed to detect essential proteins from PPI networks. However, most of the current approaches focus mainly on the topologica...
Year
DOI
Venue
2018
10.1109/TCBB.2016.2615931
IEEE/ACM Transactions on Computational Biology and Bioinformatics
Keywords
Field
DocType
Proteins,Network topology,Gene expression,Ontologies,Simulation,Electronics packaging
Ontology (information science),Computer science,Gene ontology,Gene expression,Centrality,Network topology,GATAD2B,Betweenness centrality,Bioinformatics,Protein function prediction
Journal
Volume
Issue
ISSN
15
1
1545-5963
Citations 
PageRank 
References 
1
0.37
0
Authors
4
Name
Order
Citations
PageRank
Zhang Wei139253.03
Xu Jia2111.19
Yuanyuan Li314821.33
Xiufen Zou427225.44