Title
Pattern recognition reveals characteristic postprandial glucose changes: Non-individualized meal detection in diabetes mellitus type 1.
Abstract
Accurate continuous glucose monitoring (CGM) is essential for fully automated glucose control in diabetes mellitus type 1. State-of-the-art glucose control systems automatically regulate the basal insulin infusion. Users still need to manually announce meals to dose the prandial insulin boluses. An automated meal detection could release the user and improve the glucose regulation. In this study, patterns in the postprandial CGM data are exploited for meal detection. Binary classifiers are trained to recognize the postprandial pattern in horizons of the estimated glucose rate of appearance and in CGM data. The appearance rate is determined by moving horizon estimation based on a simple model. Linear discriminant analysis (LDA) is used for classification. The proposed method is compared to methods that detect meals when thresholds are violated. Diabetes care data from 12 free-living pediatric patients was downloaded during regular screening. Experts identified meals and their start by retrospective evaluation. The classification was tested by cross-validation. Compared to the threshold-based methods, LDA showed higher sensitivity to meals with a low rate of false alarms. Classifying horizons outperformed the other methods also with respect to time of detection. The onset of meals can be detected by pattern recognition based on estimated model states and consecutive CGM measurements. No individual tuning is necessary. This makes the method easily adopted in the clinical practice.
Year
DOI
Venue
2020
10.1109/JBHI.2019.2908897
IEEE journal of biomedical and health informatics
Keywords
Field
DocType
Sugar,Insulin,Biomedical measurement,Diabetes,Informatics,Pattern recognition,Estimation
Diabetes mellitus,Pattern recognition,Computer science,Clinical Practice,Postprandial,Blood sugar regulation,Artificial intelligence,Meal,Linear discriminant analysis,Type 1 diabetes,Insulin
Journal
Volume
Issue
ISSN
24
2
2168-2194
Citations 
PageRank 
References 
0
0.34
0
Authors
5
Name
Order
Citations
PageRank
Konstanze Kolle100.68
Torben Biester200.34
Sverre Christiansen300.34
Anders Fougner411.06
Øyvind Stavdahl512515.09