Title
Exploiting Multi-Level Parallelism for Stitching Very Large Microscopy Images.
Abstract
Due to the limited field of view of the microscopes, acquisitions of macroscopic specimens require many parallel image stacks to cover the whole volume of interest. Overlapping regions are introduced among stacks in order to make it possible automatic alignment by means of a 3D stitching tool. Since state-of-the-art microscopes coupled with chemical clearing procedures can generate 3D images whose size exceeds the Terabyte, parallelization is required to keep stitching time within acceptable limits. In the present paper we discuss how multi-level parallelization reduces the execution times of TeraStitcher, a tool designed to deal with very large images. Two algorithms performing dataset partition for efficient parallelization in a transparent way are presented together with experimental results proving the effectiveness of the approach that achieves a speedup close to 300x, when both coarse- and fine-grained parallelism are exploited. Multi-level parallelization of TeraStitcher led to a significant reduction of processing times with no changes in the user interface, and with no additional effort required for the maintenance of code.
Year
DOI
Venue
2019
10.3389/fninf.2019.00041
FRONTIERS IN NEUROINFORMATICS
Keywords
Field
DocType
3D microscopy,stitching,terabyte images,parallel processing,data partitioning,GPU
Field of view,Data mining,Image stitching,Stack (abstract data type),Computer science,Terabyte,Parallel computing,Software maintenance,Microscopy,User interface,Speedup
Journal
Volume
ISSN
Citations 
13
1662-5196
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Alessandro Bria15710.63
Massimo Bernaschi250464.27
Massimiliano Guarrasi300.68
Giulio Iannello441446.75