Title
Two-Stream Compare and Contrast Network for Vertebral Compression Fracture Diagnosis
Abstract
Differentiating Vertebral Compression Fractures (VCFs) associated with trauma and osteoporosis (benign VCFs) or those caused by metastatic cancer (malignant VCFs) is critically important for treatment decisions. So far, automatic VCFs diagnosis is solved in a two-step manner, i.e., first identify VCFs and then classify them into benign or malignant. In this paper, we explore to model VCFs diagnosis as a three-class classification problem, i.e., normal vertebrae, benign VCFs, and malignant VCFs. However, VCFs recognition and classification require very different features, and both tasks are characterized by high intra-class variation and high inter-class similarity. Moreover, the dataset is extremely class-imbalanced. To address the above challenges, we propose a novel Two-Stream Compare and Contrast Network (TSCCN) for VCFs diagnosis. This network consists of two streams, a recognition stream which learns to identify VCFs through comparing and contrasting between adjacent vertebrae, and a classification stream which compares and contrasts between intra-class and inter-class to learn features for fine-grained classification. The two streams are integrated via a learnable weight control module which adaptively sets their contribution. TSCCN is evaluated on a dataset consisting of 239 VCFs patients and achieves the average sensitivity and specificity of 92.56% and 96.29%, respectively.
Year
DOI
Venue
2021
10.1109/TMI.2021.3080991
IEEE Transactions on Medical Imaging
Keywords
DocType
Volume
Fractures, Compression,Humans,Magnetic Resonance Imaging,Osteoporosis,Spinal Fractures,Spine
Journal
40
Issue
ISSN
Citations 
9
0278-0062
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Shixiang Feng101.01
Beibei Liu2111.25
Ya Zhang3134091.72
Xiaoyun Zhang417325.90
Yuehua Li500.34