Title
Deep Learning Methods for Lung Cancer Segmentation in Whole-Slide Histopathology Images—The ACDC@LungHP Challenge 2019
Abstract
Accurate segmentation of lung cancer in pathology slides is a critical step in improving patient care. We proposed the ACDC@LungHP (Automatic Cancer Detection and Classification in Whole-slide Lung Histopathology) challenge for evaluating different computer-aided diagnosis (CADs) methods on the automatic diagnosis of lung cancer. The ACDC@LungHP 2019 focused on segmentation (pixel-wise detection) of cancer tissue in whole slide imaging (WSI), using an annotated dataset of 150 training images and 50 test images from 200 patients. This paper reviews this challenge and summarizes the top 10 submitted methods for lung cancer segmentation. All methods were evaluated using metrics using the precision, accuracy, sensitivity, specificity, and DICE coefficient (DC). The DC ranged from 0.7354±0.1149 to 0.8372±0.0858. The DC of the best method was close to the inter-observer agreement (0.8398±0.0890). All methods were based on deep learning and categorized into two groups: multi-model method and single model method. In general, multi-model methods were significantly better (p<; 0.01) than single model methods, with mean DC of 0.7966 and 0.7544, respectively. Deep learning based methods could potentially help pathologists find suspicious regions for further analysis of lung cancer in WSI.
Year
DOI
Venue
2021
10.1109/JBHI.2020.3039741
IEEE Journal of Biomedical and Health Informatics
Keywords
DocType
Volume
Deep Learning,Diagnosis, Computer-Assisted,Humans,Lung Neoplasms
Journal
25
Issue
ISSN
Citations 
2
2168-2194
1
PageRank 
References 
Authors
0.35
0
15
Name
Order
Citations
PageRank
Zhang Li121.43
Jiehua Zhang210.35
Tao Tan34610.25
Xichao Teng411.37
Xiaoliang Sun5174.20
Hong Zhao65012.51
Yi Jiang75010.64
Li Yu814425.48
Zhihong Liu9104.39
Daiqiang Li1010.35
Peter J. Schüffler11497.40
Qifeng Yu128914.86
Hui Chen13228.47
Yuling Tang1410.69
Geert Litjens1599650.79