Title
iASiS Open Data Graph: Automated Semantic Integration of Disease-Specific Knowledge
Abstract
In biomedical research, unified access to up-to-date domain-specific knowledge is crucial, as such knowledge is continuously accumulated in scientific literature and structured resources. Identifying and extracting specific information is a challenging task and computational analysis of knowledge bases can be valuable in this direction. However, for disease-specific analyses researchers often need to compile their own datasets, integrating knowledge from different resources, or reuse existing datasets, that can be out-of-date. In this study, we propose a framework to automatically retrieve and integrate disease-specific knowledge into an up-to-date semantic graph, the iASiS Open Data Graph. This disease-specific semantic graph provides access to knowledge relevant to specific concepts and their individual aspects, in the form of concept relations and attributes. The proposed approach is implemented as an open-source framework and applied to three diseases (Lung Cancer, Dementia, and Duchenne Muscular Dystrophy). Exemplary queries are presented, investigating the potential of this automatically generated semantic graph as a basis for retrieval and analysis of disease-specific knowledge.
Year
DOI
Venue
2020
10.1109/CBMS49503.2020.00049
2020 IEEE 33rd International Symposium on Computer-Based Medical Systems (CBMS)
Keywords
DocType
ISSN
biomedical knowledge,knowledge graphs,semantic integration,disease-specific,biomedical literature
Conference
2372-918X
ISBN
Citations 
PageRank 
978-1-7281-9430-1
0
0.34
References 
Authors
10
4
Name
Order
Citations
PageRank
Anastasios Nentidis154.48
Konstantinos Bougiatiotis232.08
Anastasia Krithara318015.63
Georgios Paliouras41510120.93