Title | ||
---|---|---|
A Low-drift Extended-Gate Field Effect Transistor (EGFET) with Differential Amplifier for Cordyceps Sinensis DNA Detection Optimized by g<inf>m</inf>/I<inf>D</inf> Theory |
Abstract | ||
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An extended-gate field effect transistor (EGFET) integrated with a differential MOSFET amplifier and an open-source Arduino Yun MCU system was realized for detection of Cordyceps Sinensis DNA molecules. A gold microelectrode chip coated with a single-stranded DNA probe, as the extended gate was fabricated by MEMS fabrication processes. The differential MOSFET amplifier and additional coating of alkyl-thiol reduced the drifting by one order of magnitude. Moreover, generalized g
<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</sub>
/I
<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</sub>
theory was used to study the optimized working regime of the EGFET sensor. The highest electric-electrochemical sensitivity could be achieved in the Moderate Inversion (MI) regime. The sensitivity and limit of detection (LOD) of the EGFET sensor were obtained to be 13.85mV/dec and 10nM, respectively. This low-cost low-drift EGFET sensor system is promising for Internet of Living Things in the near future. |
Year | DOI | Venue |
---|---|---|
2020 | 10.1109/NEMS50311.2020.9265621 | 2020 IEEE 15th International Conference on Nano/Micro Engineered and Molecular System (NEMS) |
Keywords | DocType | ISSN |
Internet of Living Things,MI regime,moderate inversion regime,Cordyceps Sinensis DNA detection,generalized gm-ID theory,low-drift EGFET sensor system,coating,MEMS fabrication processes,extended-gate field effect transistor,single-stranded DNA probe,microelectrode chip,Cordyceps Sinensis DNA molecules,open-source Arduino Yun MCU system,differential MOSFET amplifier,low-drift extended-gate field effect transistor | Conference | 2474-3747 |
ISBN | Citations | PageRank |
978-1-7281-7231-6 | 0 | 0.34 |
References | Authors | |
0 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Yifan Xu | 1 | 0 | 0.34 |
Hadi Tavakkoli | 2 | 0 | 0.34 |
Jingting Xu | 3 | 0 | 0.34 |
Yi-Kuen Lee | 4 | 7 | 11.16 |