Title
A Low-drift Extended-Gate Field Effect Transistor (EGFET) with Differential Amplifier for Cordyceps Sinensis DNA Detection Optimized by g<inf>m</inf>/I<inf>D</inf> Theory
Abstract
An extended-gate field effect transistor (EGFET) integrated with a differential MOSFET amplifier and an open-source Arduino Yun MCU system was realized for detection of Cordyceps Sinensis DNA molecules. A gold microelectrode chip coated with a single-stranded DNA probe, as the extended gate was fabricated by MEMS fabrication processes. The differential MOSFET amplifier and additional coating of alkyl-thiol reduced the drifting by one order of magnitude. Moreover, generalized g <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</sub> /I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</sub> theory was used to study the optimized working regime of the EGFET sensor. The highest electric-electrochemical sensitivity could be achieved in the Moderate Inversion (MI) regime. The sensitivity and limit of detection (LOD) of the EGFET sensor were obtained to be 13.85mV/dec and 10nM, respectively. This low-cost low-drift EGFET sensor system is promising for Internet of Living Things in the near future.
Year
DOI
Venue
2020
10.1109/NEMS50311.2020.9265621
2020 IEEE 15th International Conference on Nano/Micro Engineered and Molecular System (NEMS)
Keywords
DocType
ISSN
Internet of Living Things,MI regime,moderate inversion regime,Cordyceps Sinensis DNA detection,generalized gm-ID theory,low-drift EGFET sensor system,coating,MEMS fabrication processes,extended-gate field effect transistor,single-stranded DNA probe,microelectrode chip,Cordyceps Sinensis DNA molecules,open-source Arduino Yun MCU system,differential MOSFET amplifier,low-drift extended-gate field effect transistor
Conference
2474-3747
ISBN
Citations 
PageRank 
978-1-7281-7231-6
0
0.34
References 
Authors
0
4
Name
Order
Citations
PageRank
Yifan Xu100.34
Hadi Tavakkoli200.34
Jingting Xu300.34
Yi-Kuen Lee4711.16