Title
PreTP-EL: prediction of therapeutic peptides based on ensemble learning
Abstract
Therapeutic peptides are important for understanding the correlation between peptides and their therapeutic diagnostic potential. The therapeutic peptides can be further divided into different types based on therapeutic function sharing different characteristics. Although some computational approaches have been proposed to predict different types of therapeutic peptides, they failed to accurately predict all types of therapeutic peptides. In this study, a predictor called PreTP-EL has been proposed via employing the ensemble learning approach to fuse the different features and machine learning techniques in order to capture the different characteristics of various therapeutic peptides. Experimental results showed that PreTP-EL outperformed other competing methods. Availability and implementation: A user-friendly web-server of PreTP-EL predictor is available at http://bliulab.net/PreTP-EL.
Year
DOI
Venue
2021
10.1093/bib/bbab358
BRIEFINGS IN BIOINFORMATICS
Keywords
DocType
Volume
therapeutic peptides, ensemble learning, genetic algorithm
Journal
22
Issue
ISSN
Citations 
6
1467-5463
1
PageRank 
References 
Authors
0.36
0
4
Name
Order
Citations
PageRank
Yichen Guo111.04
Ke Yan210.36
Hongwu Lv311.04
Bin Liu441933.30