Title
Intracerebral Haemorrhage Growth Prediction Based on Displacement Vector Field and Clinical Metadata
Abstract
Intracerebral hemorrhage (ICH) is the deadliest type of stroke. Early prediction of stroke lesion growth is crucial in assisting physicians towards better stroke assessments. Existing stroke lesion prediction methods are mainly for ischemic stroke. In ICH, most methods only focus on whether the hematoma will expand but not how it will develop. This paper explored a new, unknown topic of predicting ICH growth at the image-level based on the baseline non-contrast computerized tomography (NCCT) image and its hematoma mask. We propose a novel end-to-end prediction framework based on the displacement vector fields (DVF) with the following advantages. 1) It can simultaneously predict CT image and hematoma mask at follow-up, providing more clinical assessment references and surgery indication. 2) The DVF regularization enforces a smooth spatial deformation, limiting the degree of the stroke lesion changes and lowering the requirement of large data. 3) A multi-modal fusion module learns high-level associations between global clinical features and spatial image features. Experiments on a multi-center dataset demonstrate improved performance compared to several strong baselines. Detailed ablation experiments are conducted to highlight the contributions of various components.
Year
DOI
Venue
2021
10.1007/978-3-030-87240-3_71
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2021, PT V
Keywords
DocType
Volume
Hemorrhage growth prediction, Displacement vector field, Clinical metadata, Multi-modal fusion, DNN, Stroke
Conference
12905
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
0
8
Name
Order
Citations
PageRank
Ting Xiao100.34
Han Zheng200.34
Xiaoning Wang371.15
Xinghan Chen400.34
Jianbo Chang501.35
Jianhua Yao61135110.49
Hong Shang712.71
Peng Liu8105.18