Paper Info
Title
Ultrasound-based method for individualized estimation of central aortic blood pressure from flow velocity and diameter
Abstract
Central aortic blood pressure (CABP) is a better predictor for cardiovascular events than brachial blood pressure. However, direct CABP measurement is invasive. The objective of this paper is to develop an ultrasound-based method using individualized Windkessel (WK) models for non-invasive estimation of CABP. Three WK models (with two-, three-and four-element WK, named, WK2, WK3 and WK4, respectively) were created and the model parameters were individualized based on aortic flow velocity and diameter waveforms measured by ultrasound (US). Experimental data were acquired in 42 subjects aged 21-67 years. The CABP estimated by WK models was compared with the reference CABP obtained using a commercial system. The results showed that the overall performance of the WK3 and WK4 models was similar, outperforming the WK2 model. The estimated CABP based on WK3/WK4 model showed good agreement with the reference CABP: the absolute errors of systolic blood pressure (SBP), 2.4 +/- 2.1/2.4 +/- 2.0 mmHg; diastolic blood pressure (DBP), 1.4 +/- 1.1/1.7 +/- 1.5 mmHg; mean blood pressure (MBP), 1.3 & PLUSMN; 0.8/1.3 +/- 0.8 mmHg; pulse pressure (PP), 3.0 & PLUSMN; 2.3/3.2 +/- 2.6 mmHg; the root mean square error (RMSE) of the waveforms, 2.5 +/- 1.0/2.6 +/- 1.1 mmHg. Therefore, the proposed method can provide a non-invasive CABP estimation during routine cardiac US examination.
Year
DOI
Venue
2022
10.1016/j.compbiomed.2022.105254
COMPUTERS IN BIOLOGY AND MEDICINE
Keywords
DocType
Volume
Central aortic blood pressure, Ultrasound, Windkessel models, Aortic flow velocity, Aortic diameter
Journal
143
ISSN
Citations 
PageRank 
0010-4825
0
0.34
References 
Authors
0
9
Name
Order
Citations
PageRank
Shuran Zhou102.03
Yang Yao201.01
Wenyan Liu300.68
Jun Yang43627.68
Junli Wang500.34
Liling Hao601.35
Lu Wang7254.50
Lisheng Xu817839.09
Albert Avolio93216.60