Title
An Individually Controlled Multitined Expandable Electrode Using Active Cannula-Based Shape Morphing for On-Demand Conformal Radiofrequency Ablation Lesions
Abstract
Being minimally invasive and highly effective, radiofrequency ablation (RFA) is widely used for small-sized malignant tumor treatment. However, in clinical practice, a large number of tumors are found in irregular shape, while the current RFA devices are hard to control the morphologic appearance of RFA lesions on demand, which usually ends up with unnecessarily excessive tissue ablation and subsequently often brings irreversible damage to the organs' functions. Herein, active cannulas for each of the individually controlled subelectrodes to achieve an on-demand shape morphing and thus conformal RFA lesion are introduced. The target shape as well as the length of inserted subelectrodes can be precisely controlled by tuning the active stylets and cannulas. What's more, owing to independent movement and energy control of each subelectrodes, the electrode is shown to be not only efficient enough to accomplish accurate trajectory control to target tissue in a single insertion, but also adaptive enough to ablate target tissues with diverse morphologic appearances and locations. On-demand conformal ablation of target tissue is demonstrated as well under the guidance of ultrasound imaging with the device. Potentially, the RFA electrode is a promising minimally invasive treatment of malignant tumors in future clinical practice. An interactive preprint version of the article can be found at: https://www.authorea.com/doi/full/10.22541/au.164019293.38729522.
Year
DOI
Venue
2022
10.1002/aisy.202100262
ADVANCED INTELLIGENT SYSTEMS
Keywords
DocType
Volume
active cannulas, individually controlled electrodes, multitined electrodes, on-demand conformal lesions, radiofrequency ablation, shape morphing
Journal
4
Issue
Citations 
PageRank 
7
0
0.34
References 
Authors
0
8
Name
Order
Citations
PageRank
Zhiping Chai100.34
Liangxiong Lyu200.34
Menghao Pu300.34
Xianwen Chen400.34
Jiaqi Zhu577.26
Huageng Liang600.34
Han Ding749978.16
Zhigang Wu814.15