Title
MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health's H-1-NMR metabolomics data
Abstract
Motivation: H-1-NMR metabolomics is rapidly becoming a standard resource in large epidemiological studies to acquire metabolic profiles in large numbers of samples in a relatively low-priced and standardized manner. Concomitantly, metabolomics-based models are increasingly developed that capture disease risk or clinical risk factors. These developments raise the need for user-friendly toolbox to inspect new H-1-NMR metabolomics data and project a wide array of previously established risk models. Results: We present MiMIR (Metabolomics-based Models for Imputing Risk), a graphical user interface that provides an intuitive framework for ad hoc statistical analysis of Nightingale Health's H-1-NMR metabolomics data and allows for the projection and calibration of 24 pre-trained metabolomics-based models, without any pre-required programming knowledge. Availability and implementation: The R-shiny package is available in CRAN or downloadable at , together with an extensive user manual (also available as Supplementary Documents to the article).
Year
DOI
Venue
2022
10.1093/bioinformatics/btac388
BIOINFORMATICS
DocType
Volume
Issue
Journal
38
15
ISSN
Citations 
PageRank 
1367-4803
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
D Bizzarri100.34
Marcel J. T. Reinders21556104.09
M Beekman300.34
P E Slagboom400.34
E B van den Akker500.34