Title
Connectomics Annotation Metadata Standardization for Increased Accessibility and Queryability
Abstract
Neuroscientists can leverage technological advances to image neural tissue across a range of different scales, potentially forming the basis for the next generation of brain atlases and circuit reconstructions at submicron resolution, using Electron Microscopy and X-ray Microtomography modalities. However, there is variability in data collection, annotation, and storage approaches, which limits effective comparative and secondary analysis. There has been great progress in standardizing interfaces for large-scale spatial image data, but more work is needed to standardize annotations, especially metadata associated with neuroanatomical entities. Standardization will enable validation, sharing, and replication, greatly amplifying investment throughout the connectomics community. We share key design considerations and a usecase developed for metadata for a recent large-scale dataset.
Year
DOI
Venue
2022
10.3389/fninf.2022.828458
FRONTIERS IN NEUROINFORMATICS
Keywords
DocType
Volume
connectome, annotation, software, standard, queries, reproducibility
Journal
16
ISSN
Citations 
PageRank 
1662-5196
0
0.34
References 
Authors
5
6
Name
Order
Citations
PageRank
Morgan Sanchez100.34
Dymon Moore200.34
Erik C. Johnson301.35
Brock Wester400.34
Jeff W. Lichtman513412.41
William Gray-Roncal600.34