Title
Connectivity-behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability.
Abstract
Correlations between temporal fluctuations in MRI signals may reveal functional connectivity between brain regions within individual subjects. Such correlations would be especially useful indices of functional connectivity if they covary with behavioral performance or other subject variables. This study investigated whether such a relationship could be demonstrated in the context of the reading circuit in the brain. The method proved sufficiently powerful to reveal significant correlations between the reading abilities of subjects and the strength of their functional connection between left Brodmann's area 39 and Broca's area during reading. This suggests that the disconnection of the angular gyrus previously reported for dyslexic readers is part of a larger continuum in which poor (but nonimpaired readers) also show reduced connectivity to the region. In addition, it illustrates the potential power of paradigms that examine correlations between behavior and functional brain connections.
Year
DOI
Venue
2006
10.1016/j.neuroimage.2005.12.040
NeuroImage
Keywords
DocType
Volume
behavior analysis
Journal
31
Issue
ISSN
Citations 
2
1053-8119
26
PageRank 
References 
Authors
1.85
1
7
Name
Order
Citations
PageRank
Michelle Hampson117212.32
Fuyuze Tokoglu2312.28
Zhongdong Sun3261.85
Robin J Schafer4261.85
Pawel Skudlarski51309.62
John C Gore661641.36
R Todd Constable784877.34