Title
Gene Networks Viewed through Two Models
Abstract
This paper presents our computational and measurement strategy for investigating gene networks from gene expression data using state space model and dynamic Bayesian network model with nonparametric regression. These methods are applied to gene expression data based on gene knockdowns and drug responses for generating large global maps of gene regulation which will light up the geography where drug target pathways lie down.
Year
DOI
Venue
2009
10.1007/978-3-642-00727-9_8
BICoB
Keywords
Field
DocType
state space model,large global map,gene networks,gene expression data,measurement strategy,drug response,gene regulation,dynamic bayesian network model,gene network,gene knockdowns,drug target pathway,dynamic bayesian network,drug targeting,nonparametric regression
Gene,Computer science,Nonparametric regression,State-space representation,Gene expression,Regulation of gene expression,Bayesian network,Artificial intelligence,Bioinformatics,Gene regulatory network,Machine learning,Dynamic Bayesian network
Conference
Volume
ISSN
Citations 
5462
0302-9743
0
PageRank 
References 
Authors
0.34
9
5
Name
Order
Citations
PageRank
Satoru Miyano12406250.71
Rui Yamaguchi218026.49
Yoshinori Tamada320319.46
Masao Nagasaki436826.22
Seiya Imoto597584.16