Title
MRI tissue classification and bias field estimation based on coherent local intensity clustering: a unified energy minimization framework.
Abstract
This paper presents a new energy minimization method for simultaneous tissue classification and bias field estimation of magnetic resonance (MR) images. We first derive an important characteristic of local image intensities--the intensities of different tissues within a neighborhood form separable clusters, and the center of each cluster can be well approximated by the product of the bias within the neighborhood and a tissue-dependent constant. We then introduce a coherent local intensity clustering (CLIC) criterion function as a metric to evaluate tissue classification and bias field estimation. An integration of this metric defines an energy on a bias field, membership functions of the tissues, and the parameters that approximate the true signal from the corresponding tissues. Thus, tissue classification and bias field estimation are simultaneously achieved by minimizing this energy. The smoothness of the derived optimal bias field is ensured by the spatially coherent nature of the CLIC criterion function. As a result, no extra effort is needed to smooth the bias field in our method. Moreover, the proposed algorithm is robust to the choice of initial conditions, thereby allowing fully automatic applications. Our algorithm has been applied to high field and ultra high field MR images with promising results.
Year
DOI
Venue
2009
10.1007/978-3-642-02498-6_24
IPMI
Keywords
Field
DocType
different tissue,mri tissue classification,corresponding tissue,bias field,ultra high field mr,coherent local intensity clustering,unified energy minimization framework,bias field estimation,optimal bias field,new energy minimization method,high field,simultaneous tissue classification,tissue classification,energy minimization,initial condition,membership function,magnetic resonance
Cluster (physics),Pattern recognition,Computer science,Separable space,Artificial intelligence,Jaccard index,Cluster analysis,Smoothness,Membership function,Bias field,Energy minimization
Conference
Volume
ISSN
Citations 
21
1011-2499
53
PageRank 
References 
Authors
1.99
17
4
Name
Order
Citations
PageRank
Chunming Li1268398.49
Chenyang Xu258523.07
A. Anderson311713.06
John C Gore461641.36