Title | ||
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Development of a patient specific artificial tracheal prosthesis: Design, mechanical behavior analysis and manufacturing |
Abstract | ||
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There is a need to create patient specific organ replacements as there are differences in the anatomical dimensions among individuals. High failure rates in tracheal prosthesis are attributed to the lack of mechanical strength and flexibility, slow rate of growth of ciliated epithelium and leakage of interstitial fluid into the lumen. This paper proposes a methodology of design, simulations and fabrication of a patient specific artificial tracheal prosthesis for implantation to closely mimic the biomechanical properties of the natural trachea, and describes the prototype device and its materials. Results show that the patient-specific trachea prosthesis has mechanical properties approximate that of normal tracheal rings. The user centric tracheal prosthesis is demonstrated to be a promising candidate for tracheal replacement. |
Year | DOI | Venue |
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2013 | 10.1109/EMBC.2013.6610978 PubMed ID : 24111165 | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference |
Keywords | Field | DocType |
artificial organs,biomechanics,biomedical materials,biomimetics,materials properties,prototypes,anatomical dimension,ciliated epithelium slow growth rate,interstitial fluid leakage,natural trachea biomechanical properties,normal tracheal ring,patient specific artificial tracheal prosthesis development,patient specific artificial tracheal prosthesis fabrication,patient specific artificial tracheal prosthesis simulation,patient specific organ replacement,patient-specific trachea prosthesis mechanical properties,prosthesis design,prosthesis flexibility,prosthesis manufacturing,prosthesis mechanical behavior analysis,prosthesis mechanical strength,prototype device,prototype material,tracheal prosthesis failure rate,tracheal replacement,user centric tracheal prosthesis,solid modeling,fabrication,stress | Biomedical engineering,Mechanical strength,Prosthesis,Ciliated epithelium,Computer science,Trachea prosthesis,Biomechanics | Conference |
Volume | ISSN | Citations |
2013 | 1557-170X | 0 |
PageRank | References | Authors |
0.34 | 0 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Matthew Chua C H | 1 | 0 | 0.34 |
Chee-Kong Chui | 2 | 245 | 38.34 |
Bina Rai | 3 | 0 | 0.34 |
David Lau D P | 4 | 0 | 0.34 |